A member of the Grammy-nominated ensemble WildUp, Hopson has performed with the Los Angeles Philharmonic, Indianapolis Symphony, Juneau Symphony, LA Chamber Orchestra, LA Opera, LA Master Chorale, Pasadena Symphony & POPS, Long Beach Symphony, ReCollective Orchestra, and Southeast Symphony.  An alumnus of the Academy Awards Orchestra, Spoleto Festival USA, Coachella Festival, Ojai Music Festival, La Jolla Music Society SummerFest, Lincoln Center Festival, and Hear Now Music Festival, he made his Kennedy Center debut in the 2023 RiverRun Festival.

Hopson has performed alongside and recorded for a vast range of artists, including:

 John Adams, Adele, Andy Akiho, Lorne Balfe, Billie Eilish, Dirty Projectors, Alan Gilbert, John Debney, Lamont Dozier, Earth Wind & Fire, Danny Elfman, Peter Eötvös, Rhiannon Giddens, Robert Glasper, Chaka Khan, Alicia Keys, Seth MacFarlane, Ricky Martin, Ellen Reid, Rihanna, Craig Robinson, The Roots, Kaija Saariaho, John Williams, Stevie Wonder, and more. He has performed on 100+ film and television soundtracks, including: Beetlejuice Beetlejuice, Transformers: Rise of the Beasts, Avatar: The Way of Water, NOPE, Encanto, Coming 2 America, Men In Black: International, Big Eyes, and Kedi.

Hopson produces arts programs, strategic plans, and legislation for culture organizations, government agencies, and artists in the United States and abroad. He is currently developing a record label in Jordan to support refugee-artists across the Middle East. He has presented masterclasses and guest lectures at The Juilliard School, USC, Butler University, CalArts, and Music Academy of the West.